Shim-pack NovaCore C18-HB 5.0µm, 3.0x30mm

Part No.: 227-32904-04

Part No.: 227-32902-06

Part No.: 227-32904-01

Part No.: 227-31209-02

Shim-pack Scepter Claris features a column body with a newly-developed bioinert coating packed with Scepter series stationary phases. Bioinert coating is applied to the column body and stainless steel frit Ideal for analysis of metal-coordinating and hydrophobically adsorbing compounds such as nucleic acids, proteins, and lipids Outstanding pH and lifetime stability due to Scepter organic silica hybrid packing   Superior Sensitivity and Separation Performance in Nucleic Acid Analysis Shim-pack Scepter Claris C18-120 with the bioinert coating and Scepter C18-120 with traditional stainless steel hardware were compared in this example of an analysis of a synthetic oligonucleotide. Results from Claris were highly sensitive and reproducible from the rst injection, with no loss of sample signal. Scepter C18-120 in a stainless steel column body produced low-sensitivity results and showed adsorption from the first sample injection. Outstanding Performance in Oligonucleic Acid Analysis Shim-pack Scepter Claris C18-120 (bioinert coating) and Scepter C18-20 (stainless steel body) were compared in this analysis of Oligodeoxythymidylic acid [d(T)20]. Results from Scepter C18-120 show low peak intensity, suggesting adsorption on metal surfaces. In contrast, Scepter Claris C18-120 produced a sharper and high-intensity peak. Improved Sensitivity and Separation of Phospholipids Shim-pack Scepter Claris C18-120 minimizes metal-mediated adsorption and hydrophobic absorption on the column surfaces, resulting in high-resolution separations. In this example of structurally complex phosphatidylcholine isomers, Scepter Claris C18-120 achieved increased baseline resolution between isomers with higher sensitivity.  

Part No.: 227-32801-03

Unprecedented Resolution and Peak Shape of Basic Compounds Even for LC columns that claim to be designed for basic compounds, adequate resolution often can not be obtained due to problems such as leading of highly polar basic compounds, peak shape deterioration of acidic compounds, or long equilibration time required for low ionic strength acidic mobile phase. All of these issues have been solved with Shim-pack Arata that was specifically designed to give unmatched peak shape for basic compounds. Unmatched Peak Shape Elegantly Designed for A Wide Range of Compounds Unmatched peak shape of basic compounds could be achieved while maintaining good peak shape for acidic compounds with Shim-pack Arata LC columns. Even with low ionic strength acidic mobile phase, such as 0.1% formic acid containing mobile phase, excellent peak shape of both amitriptyline (a basic compound) and benzoic acid (an acidic compound) could be achieved. Excellent Separation Performance for Peptides Even with Weak Ion Paring Acids In order to obtain good peak shape of peptides under reversed phase chromatography, TFA containing mobile phases are frequently used which the ion pairing effect is relatively strong. However, TFA could cause ion suppression in LC/MS (/MS) analysis. Excellent peak shape and separation performance for peptides could be achieved on the Shim-pack Arata LC column even with 0.1 % formic acid (weak ion paring acid) containing mobile phase.